Publications by authors named "H Sijbrand Hofker"
Objective: To determine the nationwide use and outcome of tailored surgical treatment for symptomatic chronic pancreatitis (CP) as advised by recent guidelines.
Summary Background Data: Randomized trials have shown that surgery is superior to endoscopy in patients with symptomatic CP, although endoscopy remains popular Recent guidelines advice to "tailor surgery" based on pancreatic morphology meaning that the least extensive procedure should be selected based on pancreatic morphology. However, nationwide, and multicenter studies On tailored surgery for symptomatic CP are lacking.
Article Synopsis
- Kidney extraction time negatively impacts post-transplant outcomes; this study investigates using hydrogen sulphide (HS) in the flush medium to reduce ischemic injury.
- 22 porcine kidneys were studied in different groups based on whether the pigs underwent brain death or a sham operation, with some receiving HS treatment during extraction.
- Results showed lower pro-inflammatory cytokines in HS-treated kidneys, but no significant differences in overall renal function or injury markers between the groups, indicating potential benefits of HS without compromising other factors.
Following cold aortic flush in a deceased organ donation procedure, kidneys never reach the intended 0-4°C and stay ischemic at around 20°C in the donor's body until actual surgical retrieval. Therefore, organ extraction time could have a detrimental influence on kidney transplant outcome. We analyzed the association between extraction time and kidney transplant outcome in multicenter data of 5,426 transplant procedures from the Dutch Organ Transplantation Registry (NOTR) and 15,849 transplant procedures from the United Network for Organ Sharing (UNOS).
View Article and Find Full Text PDFBackground: Informed consent for living kidney donation is paramount, as donors are healthy individuals undergoing surgery for the benefit of others. The informed consent process for living kidney donors is heterogenous, and the question concerns how well they are actually informed. Knowledge assessments, before and after donor education, can form the basis for a standardized informed consent procedure for live kidney donation.
View Article and Find Full Text PDFPurpose Of Review: Intestinal failure secondary to short bowel syndrome is still a very serious condition. Treatment consists of parenteral nutrition to provide nutrients and maintain body weight. During the last decades, intestinal lengthening procedures have become more available.
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