Publications by authors named "H Sieme"
Article Synopsis
- The study compares the neonatal health and development of foals born from mares with ultrasonographically assessed placental abnormalities (UPA) to those born from healthy mares in the same warmblood stud.
- Foals from UPA mares displayed shorter gestation lengths and lower birth weights, along with poorer colostrum quality, affecting their immunoglobulin G levels and leading to more frequent administration of foreign plasma compared to foals from healthy mares.
- Additionally, 8.1% of foals from UPA pregnancies exhibited maladjustment syndrome, whereas none in the control group did, indicating potential health risks associated with placental disease.
Background: Fragile foal syndrome (FFS) or warmblood FFS Type 1 (WFFS) is a recessive, autosomal, hereditary, genetic defect causing late abortions, stillbirths and non-viable foals. Whether early pregnancy losses occur is unknown.
Objectives: To investigate how WFFS affects pregnancies and whether early pregnancy losses occur in WFFS matings and if there is a difference in pregnancy success between matings where both parents were allele carriers and those where only mare or stallion were WFFS carriers.
Article Synopsis
- The study focused on isolating and characterizing specific bacteriophages (phages) that target a certain type of bacteria known as subspecies, which can infect horses and humans.
- Researchers isolated 13 lytic phages, with two showing broad host ranges and effectiveness, while further tests indicated potential for bacterial growth reduction in certain conditions.
- Although phages did not significantly reduce bacterial growth in all experiments, their interactions with bacteria suggest they could be developed into a promising antimicrobial treatment with further optimization and research.
Oocyte cryopreservation is increasingly being used in reproductive technologies for conservation and breeding purposes. Further development of oocyte cryopreservation techniques requires interdisciplinary insights in the underlying principles of cryopreservation. This review aims to serve this purpose by: (1) highlighting that preservation strategies can be rationally designed, (2) presenting mechanistic insights in volume and osmotic stress responses associated with CPA loading strategies and cooling, and (3) giving a comprehensive listing of oocyte specific biophysical membrane characteristics and commonly used permeation model equations.
View Article and Find Full Text PDFLittle is known about the incidence and outcome of high-risk pregnancies in equine practice and clinical studies on spontaneous occurring placentitis cases and treatments are missing. Therefore, the aims of this retrospective field study were to (1) describe the incidence and severity of ultrasonographic assessed placental abnormalities (UPA) in 4,192 pregnancies on a large commercial warmblood stud farm in 2017 - 2019 and (2) characterize these UPA cases and their pregnancy outcome. UPA severity (Placental abnormality score (PSc) 1-3; low to high), nine treatment regimens (TM1-9) used in UPA cases and treatment duration as well as subsequent fertility were analyzed in the group of UPA mares.
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