Publications by authors named "H Siddons"

Background And Aims: Apomixis in plants generates clonal progeny with a maternal genotype through asexual seed formation. Hieracium subgenus Pilosella (Asteraceae) contains polyploid, highly heterozygous apomictic and sexual species. Within apomictic Hieracium, dominant genetic loci independently regulate the qualitative developmental components of apomixis.

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The Hieracium and Pilosella (Lactuceae, Asteraceae) genera of closely related hawkweeds contain species with two different modes of gametophytic apomixis (asexual seed formation). Both genera contain polyploid species, and in wild populations, sexual and apomictic species co-exist. Apomixis is known to co-exist with sexuality in apomictic Pilosella individuals, however, apomictic Hieracium have been regarded as obligate apomicts.

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Article Synopsis
  • Apomixis in Hieracium praealtum, a type of asexual reproduction, is regulated by two dominant genes, one of which is called the LOSS OF APOMEIOSIS (LOA) locus.
  • The LOA locus is crucial for starting apomixis, creating embryo sacs without meiosis (apospory), and inhibiting sexual reproduction, with its structure featuring extensive repeating sequences along the chromosome.
  • Research using fluorescence in situ hybridization (FISH) demonstrated that the LOA locus can be isolated from these repetitive sequences, indicating that these repeats are not necessary for the process of apospory or preventing female meiosis.
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Objective: To examine the effectiveness of a cognitive-behavioural therapy (CBT) group intervention to facilitate improved psycho-sexual adjustment to treatment side effects in prostate cancer survivors post-radical prostatectomy.

Methods: A randomised, wait-list controlled trial was conducted with a total of 60 men who participated in a manualised 8-week cognitive-behavioural group intervention 6 months to 5 years post-radical prostatectomy for localised prostate cancer. Participants completed standardised questionnaires pre-intervention and post-intervention, which assessed mood state, stress, general and prostate cancer anxiety, quality of life and areas of sexual functioning.

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Purpose: This study aims to explore the experiences of patients enrolled in a cancer-related clinical drug treatment trial utilising a qualitative focus-group methodology. Specifically, this study aimed to explore the impact of social and family support, the challenges and advantages of taking part in a clinical trial and the experiences of patients at the conclusion of the trial.

Methods: A qualitative study was conducted at a public hospital in Melbourne in 2008.

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