Publications by authors named "H Shuto"
Background: Distinguishing infection and colonization from respiratory samples is challenging. We aimed to determine useful markers for differentiating infection from colonization in community-acquired pneumonia (CAP) patients.
Methods: We included CAP patients in whom was isolated from sputum but were not initially treated with targeting antibiotics.
Hemodialysis patients are at high risk for developing pneumonia (PJP), and trimethoprim-sulfamethoxazole (TMP-SMX) is the first-line agent for treating this disease. However, there is a lack of consensus on the required dosage of TMP-SMX for hemodialysis patients. This study used the nationwide Japanese Diagnosis Procedure Combination database to review hemodialysis patients hospitalized for PJP from April 2014 to March 2022.
View Article and Find Full Text PDFPurpose: Although the international guidelines for managing bronchiectasis are centred on preventing the exacerbation of bronchiectasis, the medical causes of admissions to hospital among patients with bronchiectasis have not been fully investigated.
Methods: This study targeted patients with bronchiectasis who were admitted to hospitals between April 2018 and March 2020 using the national inpatient database in Japan. The causes of hospitalisation and types of antibiotics used for hospitalised patients were recorded.
Article Synopsis
- * Pseudomonas aeruginosa was the most common bacterium found, present in 29.2% of cases, followed by MRSA (12.0%) and Klebsiella spp. (9.5%).
- * The analysis revealed a high prevalence of multidrug-resistant (MDR) pathogens, with 57.8% detected, emphasizing the importance of this data for choosing effective treatment options.
Background: Carbapenem is recommended as one of the first-line regimens for ventilator-associated pneumonia (VAP), but no recent systematic review has fully investigated its efficacy. This systematic review aims to evaluate the efficacy of carbapenem compared with non-carbapenem for VAP treatment.
Methods: We performed a systematic review and meta-analysis of studies comparing the efficacy and the safety between carbapenem and non-carbapenem with activity to Pseudomonas aeruginosa in the treatment for VAP.