Analysing expression of loneliness and insomnia through social intelligence analysis.

Background: Loneliness and insomnia are mutually occurring conditions. This paper investigates whether keywords depicting loneliness and insomnia are expressed together on social media. Understanding loneliness through data fills the gaps or validates the literature on loneliness from sociological and psychological perspectives.

Implementation of a Digital Health Technology Platform Improves Neurosurgical Resident Communication Skills.

Introduction: Surgical residency lacks standardized curricula for teaching interpersonal and communication skills. We evaluated the utility of a digital health communication platform, Playback Health, that generates audiovisual recordings of patient-provider interactions as a tool for junior neurosurgical resident education.

Methods: Junior (postgraduate year (PGY)-2 and PGY-3) neurosurgical residents rated their comfort working with five attending neurosurgeons (one of whom implemented Playback Health) across 10 categories, grouped into three overarching domains encompassing knowledge base, technical skills, and interpersonal skills on a 10-point Likert scale.

Beyond Chemistry: Investigating the Physical, Pharmacological, and Computational Aspects of Polyoxometalate Integrated Solid Lipid Nanoparticles for Cancer Treatment.

Purpose: The solid lipid nanoparticles of transitional metal complexes (POMs) were prepared with natural lipids with the aim of developing a safer therapeutic approach for cancer treatment.

Methods: Natural lipids were used to create solid lipid nanoparticles containing transitional metal complexes (POMs).

Results: The nanoparticles had displayed appreciable entrapment and loading percentage of PW.

Evaluation of two methods for counting residual leukocytes in leukoreduced packed red cells: Flow cytometry and fully automated cell counter.

Background And Objectives: Objective of the study is to explore the possibility of utilization of seven part fully automated hematology analyzer for enumeration of residual leukocytes (residual white blood cells [rWBCs]) in leukoreduced packed red cells (LR-PRCs) prepared from whole blood at a blood center as an alternate to the gold standard method, flow cytometry. In this study, we evaluate the performance characteristic of hematology analyzer against flow cytometry for the estimation of rWBCs in 39 LR-PRC units.

Materials And Methods: PRCs prepared from whole blood donations by 39 donors were leukoreduced and their volumes were noted.

Towards linking histological changes to liver viscoelasticity: a hybrid analytical-computational micromechanics approach.

Motivated by elastography that utilizes tissue mechanical properties as biomarkers for liver disease, with the eventual objective of quantitatively linking histopathology and bulk mechanical properties, we develop a micromechanical modeling approach to capture the effects of fat and collagen deposition in the liver. Specifically, we utilize computational homogenization to convert the microstructural changes in hepatic lobule to the effective viscoelastic modulus of the liver tissue, i.e.