Publications by authors named "H Sethi"
Article Synopsis
- Falciform ligament abscess (FLA) is an uncommon condition that can arise from local inflammation.
- The case discussed involved a patient who developed FLA following cholangitis and a laparoscopic cholecystectomy that led to a superficial umbilical wound infection.
- The diagnosis was made through clinical examination and CT imaging, and the condition was treated with laparoscopic drainage.
Early in Alzheimer's disease (AD), pericytes constrict capillaries, increasing their hydraulic resistance and trapping of immune cells and, thus, decreasing cerebral blood flow (CBF). Therapeutic approaches to attenuate pericyte-mediated constriction in AD are lacking. Here, using in vivo two-photon imaging with laser Doppler and speckle flowmetry and magnetic resonance imaging, we show that Ca entry via L-type voltage-gated calcium channels (CaVs) controls the contractile tone of pericytes.
View Article and Find Full Text PDFBackground: In early breast cancer (EBC) patients, we aimed to determine whether circulating tumor DNA (ctDNA) analysis following primary surgery, before systemic therapy, identified molecular residual disease and was associated with risk of relapse and relapse-free survival (RFS).
Methods: Plasma was collected, retrospectively, before surgery, 1-14 weeks post-operatively, and before adjuvant therapy, and in a subset of patients after adjuvant therapy. A personalized, tumor-informed, multiplex PCR next generation sequencing assay (Signatera™) was used for ctDNA detection and quantification.
Background: Triple negative breast cancer (TNBC) is an aggressive subtype with poor prognosis. We aimed to determine whether circulating tumor DNA (ctDNA) and circulating tumor cell (CTC) could predict response and long-term outcomes to neoadjuvant chemotherapy (NAC).
Methods: Patients with TNBC were enrolled between 2017-2021 at The University of Texas MD Anderson Cancer Center (Houston, TX).
Article Synopsis
- A 46-year-old male patient presented with a painful lump in his breast, which had been persistent for a year, raising suspicions of hydatid disease.
- This case is notable because hydatid disease of the breast in males hasn't been previously documented, though similarities in imaging features to female cases were observed, particularly the "water-lily" sign on ultrasound.
- The successful preoperative diagnosis through fine-needle aspiration cytology and histopathology emphasized the importance of considering hydatid disease in suspicious breast masses, helping avoid unnecessary imaging.