Publications by authors named "H Sekido"
Article Synopsis
- The traditional method for extracting nitrite from food involves slightly alkaline conditions and colorimetric analysis, but it can result in cloudy samples that are hard to filter.
- An improved analytical method has been validated, yielding target values for trueness (88-92%), repeatability (2.0-3.0%), and intralaboratory reproducibility (3.2-4.3%) in common food samples like cod roe and ham.
- An interlaboratory study across eight institutions confirmed the method's effectiveness, reporting trueness between 82-95% and repeatability of 2.3-5.8%, demonstrating the method's potential for reliable nitrite determination in food.
Article Synopsis
- The study aimed to test whether adjuvant chemotherapy for stage III colon cancer could be effectively shortened from the conventional 6 months to 3 months using the SOX regimen (S-1 and oxaliplatin).
- In a randomized phase II trial, patients received either 3 months or 6 months of SOX treatment, with the primary goal of measuring 3-year disease-free survival (DFS).
- Results showed that the 3-year DFS rates were similar for both groups (75% for 6 months and 76.9% for 3 months), indicating that shortening the treatment did not significantly improve outcomes, and the primary endpoint was not met.
[Validation Study on Migration Test for Plastic Food Utensils, Containers, and Packaging].
Shokuhin Eiseigaku Zasshi
June 2022
Migration test of food utensils, containers, and packaging is an important test method for confirming the safety and their compliance to the standards. However, there is little report on inter-laboratory study which was performed to evaluate the entire migration test, including migration operations and quantification. An interlaboratory study was performed participating 22 laboratories using 8 types of model synthetic resin samples containing 10 substances with a wide range of Log P values to evaluate the accuracy of the entire migration test.
View Article and Find Full Text PDFRegorafenib is an oral multikinase inhibitor affecting angiogenesis, oncogenesis, metastasis, and tumor immunity. As a systemic treatment, it has been shown to provide survival benefits in hepatocellular carcinoma (HCC) patients progressing on sorafenib treatment. We report herein a case of HCC with hepatic vein tumor thrombosis protruding into the inferior vena cava (IVC-HVTT) which was successfully treated by surgery following second-line chemotherapy with regorafenib.
View Article and Find Full Text PDFBackground: A drain exchange with the use of a guidewire may be accompanied by serious complications.
Case Presentation: This case involved an 86-year-old man with overlapping cancers of intrahepatic cholangiocarcinoma and perihilar cholangiocarcinoma. A left hepatectomy, a left caudal lobectomy (with a medial hepatic vein preservation), an extrahepatic bile duct resection, and a right hepatojejunostomy were performed.