Publications by authors named "H Schultheis"

While action selection strategies in well-defined domains have received considerable attention, little is yet known about how people choose what to do next in ill-defined tasks. In this contribution, we shed light on this issue by considering everyday tasks, which in many cases have a multitude of possible solutions (e.g.

View Article and Find Full Text PDF

Transcription factors (TFs) are crucial epigenetic regulators, which enable cells to dynamically adjust gene expression in response to environmental signals. Computational procedures like digital genomic footprinting on chromatin accessibility assays such as ATACseq can be used to identify bound TFs in a genome-wide scale. This method utilizes short regions of low accessibility signals due to steric hindrance of DNA bound proteins, called footprints (FPs), which are combined with motif databases for TF identification.

View Article and Find Full Text PDF

The ability to judge spatial relations from perspectives that differ from one's current body orientation and location is important for many everyday activities. Despite considerable research on imaginal perspective taking, however, detailed computational accounts of the processes involved in this ability are missing. In this contribution, I introduce Smart (Spatial Memory Access by Reference Frame SelecTion) as a computational cognitive model of imaginal perspective taking processes.

View Article and Find Full Text PDF

The sonification of data to communicate information to a user is a relatively new approach that established itself around the 1990s. To date, many researchers have designed their individual sonification from scratch. There are no standards in sonification design and evaluation.

View Article and Find Full Text PDF

Cooperativity between transcription factors is important to regulate target gene expression. In particular, the binding grammar of TFs in relation to each other, as well as in the context of other genomic elements, is crucial for TF functionality. However, tools to easily uncover co-occurrence between DNA-binding proteins, and investigate the regulatory modules of TFs, are limited.

View Article and Find Full Text PDF