Publications by authors named "H Schrader"

Article Synopsis
  • Intra-atrial shunts are linked to a higher risk of embolic strokes, and this study compares outcomes of shunt occlusion between younger (≤50 years) and older (>50 years) patients with a history of paradoxical embolism.
  • The study analyzed data from 187 patients who underwent shunt occlusion from 2013 to 2023, revealing that older patients had more cardiovascular risk factors but similar shunt characteristics and procedural outcomes compared to younger patients.
  • Follow-up results showed low recurrence rates of arterial embolism and no significant outcome differences between high-volume and low-volume shunts in older patients, suggesting similar safety and efficacy for both age groups.
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Article Synopsis
  • Percutaneous interventional left atrial appendage occlusion (LAAO) is a proven method for preventing strokes in patients with atrial fibrillation (AF) and has been evaluated in a study involving 149 patients at a Berlin hospital from 2016 to 2022.
  • The study compared two types of devices used in LAAO: single-occlusive plug-type (SOPT) and dual-occlusive disc-type (DODT), noting that while DODT procedures took longer, both had successful implantation with low rates of complications and no hospital deaths.
  • After six months, findings indicated that SOPT had a higher rate of device-related thrombus formation compared
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Introduction: There is a lack of real-world data directly comparing different valve prostheses for transaortic valve replacement (TAVR). We aimed to compare early clinical outcomes at 30-days between the self-expandable Portico valve (Abbott) with the balloon-expandable Edwards Sapien 3 valve (Edwards Lifesciences) (ES3).

Methods: Out of 1,901 patients undergoing TAVR between January 2018 and December 2021, all patients who received either Portico valve or ES3 valve via transfemoral TAVR were matched using nearest-neighbor (1:1) propensity scoring.

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Background: At the beginning of the pandemic in 2020, healthcare assistants in general practices were confronted with numerous new challenges. The aim of the study was to investigate the stress factors of healthcare assistants in March/April 2020 as well as in the further course of the pandemic in 2020.

Methods: From August to December 2020, 6,300 randomly selected healthcare assistants in four German states were invited to participate in the study.

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In ecotoxicology, evaluation of toxicities and no observed effect concentrations (NOEC) of test compounds in experimental fish is commonly based on molecular-, biochemical- and analytical chemistry analyses of organ/tissue samples and the assessment of (histo-) pathological lesions. Standardization of organ/tissue sampling locations, sample numbers, and sample processing contributes to warrant the reproducibility and inter- and intra-study comparability of analysis results. The present article provides the first comprehensive tissue sampling guidelines specifically adapted to rainbow trout (Oncorhynchus mykiss) as a frequently used fish species in ecotoxicological studies.

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