The pharmacological qualities of the D-Penicillamin and the data of immunology and especially of the collagenous metabolism of the sarcoidosis justify an investigation of the therapeutical effect of D-Penicillamin. An account is given of six patients who were suffering from sarcoidosis and of whom an effective influence over the X-ray findings was stated after a three months' dose at least. It seems to be a continuous success because after a one-to-three years' obse-vation a relapse has not occurred.
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