Publications by authors named "H Schiffl"

Background: Chronic conventional cigarette smoking has been closely linked to incident chronic kidney disease (CKD) in the general population. It is associated with the acceleration of pre-existing CKD and failure of kidney allograft function. Cessation of conventional cigarette smoking is effective in reducing the increased risk of smoking induced kidney damage.

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Article Synopsis
  • Continuous kidney replacement therapy (CKRT) is crucial for unstable adult ICU patients with severe acute kidney injury (AKI), and its success relies on achieving proper dosing according to KDIGO guidelines.
  • Current practices vary globally, with evidence suggesting that lower CKRT doses (under 20 ml/kg/h) may lead to higher mortality and that the optimal minimal effective dose remains unknown, creating a need for further research.
  • In Japan, the median delivered CKRT dose for severe AKI patients is often below recommended levels, raising questions about treatment adequacy and the need for individualized dosing in critical care settings.
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Purpose Of Review: Since the end of 2019, the coronavirus disease 2019 (COVID-19) pandemic has infected nearly 800 million people and caused almost seven million deaths. Obesity was quickly identified as a risk factor for severe COVID-19, ICU admission, acute respiratory distress syndrome, organ support including mechanical ventilation and prolonged length of stay. The relationship among obesity; COVID-19; and respiratory, thrombotic, and renal complications upon admission to the ICU is unclear.

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Purpose: The COVID-19 pandemic may have an impact on the long-term kidney function of survivors. The clinical relevance is not clear.

Methods: This review summarises the currently published data.

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