Publications by authors named "H Sanai"

Universal diagnostic criteria for chronic endometritis (CE) have not been established due to differences in study design among researchers and a lack of typical clinical cases. Lipopolysaccharides (LPSs) have been reported to cause inflammation in the reproductive systems of several animals. This study aimed to elucidate the influence of LPS in the pathogenesis of CE in humans.

View Article and Find Full Text PDF

Purpose: This study aimed to assess whether short repetition time (TR) diffusion-weighted imaging (DWI) could improve diffusion contrast in patients with prostate cancer (PCa) compared with long TR (conventional) reference standard DWI.

Materials And Methods: Our Institutional Review Board approved this retrospective study and waived the need for informed consent. Twenty-five patients with suspected PCa underwent multiparametric magnetic resonance imaging (mp-MRI) using a 3.

View Article and Find Full Text PDF
Article Synopsis
  • Classical-like Ehlers-Danlos syndrome (clEDS) is an autosomal recessive disorder linked to the absence of tenascin-X and specific genetic variations identified in 50 patients from 43 families.
  • Detecting these genetic variants is difficult due to a related pseudogene that can interfere with analysis; researchers developed a new genetic screening system to overcome this challenge.
  • This study found biallelic variants in nine new patients and noted a higher occurrence of gastrointestinal issues compared to earlier reports, emphasizing the need for increased awareness of these complications associated with clEDS.
View Article and Find Full Text PDF

Purpose: The mechanisms underlying the morphological changes in liver cirrhosis remain unknown. This study aimed to clarify the relationship between fibrotic hepatic morphology and portal hemodynamic changes using four-dimensional flow magnetic resonance imaging (MRI).

Materials And Methods: Overall, 100 patients with suspected liver disease who underwent 3-T MRI were evaluated in this retrospective study.

View Article and Find Full Text PDF

We reported a detailed obstetric course of a Japanese patient with Ehlers-Danlos syndrome (EDS) caused by biallelic pathogenic variants in the AEBP1 gene. She was diagnosed with classical EDS at 3 years of age. At 33 years, whole-exome sequencing revealed a homozygous nonsense variant (c.

View Article and Find Full Text PDF