Publications by authors named "H Samarasinghe"
Article Synopsis
- A 60-something male patient experienced worsening symptoms like confusion, paranoia, cognitive decline, and myoclonus, all while having a history of paranoid schizophrenia.
- Extensive medical tests, including blood work and brain scans (MRI), did not provide clear answers but showed abnormal brain activity and damage in specific areas.
- An electroencephalogram (EEG) revealed abnormal sharp wave discharges, indicating the patient was likely in a state of status epilepticus, a severe epileptic condition.
Article Synopsis
- Axial spondyloarthritis (axSpA) is a long-term disease that can lead to heart problems and is connected to a higher chance of diabetes.
- Researchers studied diabetes in people with axSpA to see how common it is and if they have a higher risk compared to those without the disease.
- They found that about 7% of people with axSpA have diabetes, and those with the disease are more likely to have diabetes than those without it.
From bench to bedside - is there a role of IL-17 drugs in rheumatoid arthritis?
Expert Opin Investig Drugs
June 2024
Introduction: IL-17 has been described as a pro-inflammatory cytokine that is relevant in the seronegative spondylarthritides with IL-17 targeted therapies being licensed for their treatment.There is evidence to demonstrate that IL-17 is found in RA joints and contributes to the pro-inflammatory cascade. This results in synovial hyperplasia and osteoclastogenesis thus causing joint destruction and bony erosions.
View Article and Find Full Text PDFPseudophilautus conniffae from Lowland wet zone of Sri Lanka, was described as a new species in 2019. The validity of the new species was questionable and was often challenged as it shares strong morphological resemblance with P. limbus.
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