Publications by authors named "H Sakazaki"
Article Synopsis
- Left ventricular noncompaction (LVNC) is a hereditary heart condition marked by unusual heart muscle structure, and this study specifically focused on biventricular noncompaction (BiVNC) in children to understand its clinical characteristics and genetic factors.
- The research involved 234 pediatric patients and revealed that BiVNC often leads to serious complications, including a higher incidence of congenital heart disease and reduced survival rates compared to other heart conditions.
- Findings indicated that patients with BiVNC frequently exhibited left ventricular dysfunction and a notable percentage had genetic variants linked to mitochondrial and developmental issues, emphasizing the need for thorough genetic screening for better patient outcomes.
Article Synopsis
- The document in question addresses corrections made to the original article identified by DOI: 10.3389/fcvm.2023.1212882.
- The corrections aim to address inaccuracies or errors found in the previously published research.
- These revisions ensure the integrity and reliability of the findings presented in the article.
Article Synopsis
- The study investigates the long-term outcomes of pulmonary arterial hypertension (PAH) linked to congenital heart disease (CHD) using a scoring system called the index of pulmonary vascular disease (IPVD), which categorizes lung pathology severity.
- Out of 764 patients under 20 years old with CHD-PAH, those with an IPVD score of 2.0 or higher experienced significantly worse survival rates, highlighting the relationship between IPVD scores and cardiovascular death.
- The findings suggest that the IPVD scoring system can help predict outcomes, indicating that patients with higher IPVD scores may require more careful treatment strategies, such as considering palliative measures before any surgical corrections.
Novel operative technique for Scimitar syndrome: Posterior flap technique.
Asian Cardiovasc Thorac Ann
July 2023
Various surgical techniques have been reported for Scimitar syndrome, because of the heterogenous anatomy of the disease. We developed a novel surgical method to repair Scimitar syndrome, in which, a new pulmonary venous route is constructed behind the inferior vena cava using autologous flaps of the inferior vena cava and the interatrial septum. An adult case of Scimitar syndrome was repaired by this method with good results.
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- Cardiac calmodulinopathy is a rare genetic condition that leads to dangerous heart rhythms and sudden death in young people, linked to mutations in calmodulin genes (CALM1, CALM2, CALM3).
- Researchers analyzed 195 children suspected of inherited heart conditions and found 10 with gene variants associated with calmodulinopathy, presenting various arrhythmia-related symptoms.
- Effective treatment options included beta-blockers, often combined with other medications, highlighting the importance of early diagnosis and intervention for patients.