Publications by authors named "H S SOROFF"

Each year there are over 500,000 burns that present to the emergency department (ED). Most burns are minor, and their care focuses on local wound management. The current article will present a typical case and then review the epidemiology, pathophysiology, diagnosis, and management of minor burns in the ED.

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Background: B-type natriuretic peptide (BNP) released from cardiac myocytes plays an important role in cardiac homeostasis through cyclic guanosine monophosphate (cGMP) activation. BNP also reduces cardiac remodeling and fibrosis. The antifibrotic effects of BNP are mediated in part by blocking the effects of transforming growth factor beta, a profibrotic cytokine that plays a significant role in cutaneous wound healing.

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Background: Cooling of burns is one of the oldest therapies, yet there are concerns that excessive cooling may result in hypothermia.

Objectives: To determine the effects of surface cooling with a commercially available cooling blanket on the core temperatures of volunteers and to test the ability of the cooling blanket to reduce water evaporation from plastic containers. The null hypothesis was that rectal temperatures would not be reduced by surface cooling and that the cooling blanket would reduce evaporative water loss.

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Background: Octylcyanoacrylate (OCA) is a tissue adhesive used to close wounds and to treat minor abrasions.

Objective: To explore the use of OCA in patients with superficial, partial-thickness burns.

Methods: A prospective, noncomparative, pilot study was conducted in an emergency department (ED) and burn center.

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