Publications by authors named "H S Lilja"
Background: Proton pump inhibitors (PPIs) are among the most popular drugs worldwide. Yet, there are concerns on long-term safety and poor adherence to prescription guidelines. Off-label use in children and increasing maintenance use in older adults may be particularly worrisome.
View Article and Find Full Text PDFGenetic variation at the 19q13.3 KLK locus is linked with prostate cancer susceptibility in men. The non-synonymous KLK3 single nucleotide polymorphism (SNP), rs17632542 (c.
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- The study aimed to assess the long-term effects of cloacal malformations on bowel and bladder control, sexual function, reproductive health, and quality of life in adults.
- In a Nordic multi-center study, 34 out of 48 eligible patients participated, revealing challenges like rare bowel control and reduced sexual function despite many being continent for urination.
- Although quality of life was generally comparable to the population average, significant issues were noted, especially in sexual health and fertility, highlighting the importance of ongoing follow-up for affected individuals.
Article Synopsis
- The study focuses on the role of Goblet cells and the marker REG4 in necrotizing enterocolitis (NEC) among preterm infants, comparing biopsies from infants with NEC to those without.
- Results show that REG4 expression was significantly lower in infants with NEC, suggesting a potential link between Goblet cell dysfunction and NEC risk.
- However, the study also indicates that the maturity of the infants may influence REG4 expression, complicating the interpretation of the results.