Publications by authors named "H S Khoo-Tan"
Background: In 2008, the Federation of Gynecology and Obstetrics (FIGO) revised their 1988 staging system for uterine leiomyosarcomas. In this article, we compare performance of the 2008 and 1988 FIGO systems.
Methods: Individual case data were manually culled.
Objective: Synchronous occurrence of endometrial and ovarian tumors is uncommon, and they affect less than 10% of women with endometrial or ovarian cancers. The aim of this study is to describe the epidemiological and clinical factors; and survival outcomes of women with these cancers.
Methods: This is a retrospective cohort study in a large tertiary institution in Singapore.
Objective: The use of adjuvant radiotherapy for early stage node negative patients varies for different institutions. The recognized factors such as deep stromal invasion, lymph vascular space invasion, and size of tumor are the most common factors cited for adjuvant radiotherapy. Studies done have shown that this increases local control but may increase chronic toxicity rates.
View Article and Find Full Text PDFObjective: It is our standard of care to include pelvic lymph node dissection (PLND) in the staging of endometrial cancer, followed by adjuvant vaginal vault brachytherapy. We report our experience and outcome of patients with stage 1C grade 3 endometrial cancer from KK Hospital Singapore.
Methods: Records of patients with a diagnosis of stage 1C grade 3 endometrial cancer (based on the 1988 FIGO [International Federation of Gynecology and Obstetrics] staging system) from 1995 to 2008 were retrospectively reviewed.
Article Synopsis
- This study analyzed the survival outcomes and failure patterns in 120 patients with locally advanced cervical cancer treated with high-dose rate brachytherapy and cisplatin-based chemoradiotherapy from 1999 to 2005.
- The 5-year overall survival rate was 65%, while the disease-free survival rate was 57.3%, with most recurrences occurring at distant sites.
- Significant factors impacting survival included low hemoglobin levels and tumor size, highlighting the need for further research on the safety of this treatment combination and the importance of imaging for assessing prognosis.