Publications by authors named "H S Jafri"
Introduction: The safety and efficacy of paroxysmal atrial fibrillation (PAF) ablation with the HELIOSTAR multielectrode radiofrequency (RF) balloon catheter have been demonstrated in European studies; data from elsewhere are lacking. This prospective, multicenter study conducted in the United States, Italy, and China investigated the safety and efficacy of pulmonary vein isolation (PVI) using HELIOSTAR in drug-refractory symptomatic PAF.
Methods: The primary effectiveness endpoint (PEE) was 12-month freedom from documented atrial fibrillation/atrial flutter/atrial tachycardia plus freedom from acute procedural failure, nonstudy catheter failure, repeat ablation failure, direct current cardioversion (DCCV), and Class I/III antiarrhythmic drug (AAD) failure.
Article Synopsis
- - This systematic review investigates white matter hyperintensity (WMH) research from 2000 to 2022, focusing on prevalence, mechanisms, and characteristics of studied cohorts while following PRISMA guidelines.
- - The analysis revealed 1007 visual rating scales, 118 pipeline development articles, and 509 implementation articles, with a significant focus on aging, dementia, and psychiatric disorders, and indicated that deep learning is the leading segmentation technique developed.
- - Despite advancements in quantitative techniques, traditional visual rating scales remain popular, with SPM being the most commonly used method; the review emphasizes the need for future standards in WMH segmentation and offers recommendations accordingly.
The authors have developed a paradigm using positron emission tomography (PET) with multiple radiopharmaceutical tracers that combines measurements of cerebral metabolic rate of glucose (CMRGlc), cerebral metabolic rate of oxygen (CMRO2), cerebral blood flow (CBF), and cerebral blood volume (CBV), culminating in estimates of brain aerobic glycolysis (AG). These in vivo estimates of oxidative and non-oxidative glucose metabolism are pertinent to the study of the human brain in health and disease. The latest positron emission tomography-computed tomography (PET-CT) scanners provide time-of-flight (TOF) imaging and critical improvements in spatial resolution and reduction of artifacts.
View Article and Find Full Text PDFWe study the transition to synchronization in an ensemble of chaotic oscillators that are interacting on a star network. These oscillators possess an invariant symmetry and we study emergent behavior by introducing the timescale variations in the dynamics of the nodes and the hub. If the coupling preserves the symmetry, the ensemble exhibits consecutive explosive transitions, each one associated with a hysteresis.
View Article and Find Full Text PDFBackground: Since the efficacy and safety of endovascular thrombectomy (EVT) in patients with acute ischemic stroke with a large infarct area is still inconclusive, we sought to compare functional and neurological outcomes with the use of endovascular thrombectomy versus medical care alone.
Methods: We searched MEDLINE (via PubMed), Embase, Cochrane Library, ClinicalTrials.gov, and the International Clinical Trials Registry Platform (ICTRP) to retrieve all the relevant randomized controlled trials (RCTs) on this topic.