Publications by authors named "H S Dua"
Article Synopsis
- Infectious keratitis (IK) is a major cause of corneal blindness worldwide, and the study evaluates the effectiveness of deep learning (DL) in its diagnosis compared to ophthalmologists.
- The systematic review included 35 studies with over 136,000 corneal images, finding that DL had high sensitivity (86.2%-91.6%) and specificity (90.7%-96.3%) for diagnosing IK.
- Results indicate that DL models perform similarly to ophthalmologists in diagnosing IK, but the conclusions should be approached cautiously due to potential biases and the need for further validation in diverse populations.
Keratoconus is a progressive eye disorder primarily affecting individuals in adolescence and early adulthood. The ectatic changes in the cornea cause thinning and cone-like steepening leading to irregular astigmatism and reduced vision. Keratoconus is a complex disorder with a multifaceted aetiology and pathogenesis, including genetic, environmental, biomechanical and cellular factors.
View Article and Find Full Text PDFAn integrated cell, tissue, and eye bank is vital to meet the evolving needs of ocular transplant therapies. In addition to traditional corneal transplant tissues, it encompasses processing and delivery of transplant materials for newer treatments like cell-based therapies and gene-modified products, adhering to rigorous standards, optimizing tissue utilization with comprehensive services for surgeons.
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- The study analyzed 138 patients with contact lens-related bacterial keratitis (CLBK) over a 7-year period to understand their demographics, CL wear behavior, and treatment outcomes.
- The majority of cases were linked to soft contact lenses, with Pseudomonas aeruginosa and Staphylococcus spp. being the most common bacteria found; poor hygiene was a significant factor in over half the cases.
- Most patients responded well to topical antibiotics, achieving good visual acuity, although older age, female gender, and larger infection size were associated with poorer healing outcomes.
Management of nonhealing corneal ulcers is challenging as it can lead to complications such as melting, descemetocele, and perforation, which can be prevented by amniotic membrane graft (AMG). The absence of any review (English language) on AMG for corneal ulcers prompted us to conduct this review. We looked for clinical trials (randomized and controlled) on the effect of AMG combined with other treatments, through various search engines utilizing the terms amniotic membrane and corneal ulcer.
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