Publications by authors named "H S Athar"
Article Synopsis
- Fibrosis contributes to serious damage in organs, but treatments targeting specific activators have often failed, leading researchers to focus on the leukemia inhibitory factor receptor (LIFR) as a key player in fibrotic diseases like idiopathic pulmonary fibrosis (IPF).
- In IPF, myofibroblasts highly express LIF, and fibroblasts in key fibrotic areas coexpress LIF and LIFR, demonstrating LIFR's role in amplifying signals from other fibrotic drivers like TGFβ1, IL-4, and IL-13.
- Blocking LIFR reduces the activation of profibrotic genes and highlights LIFR's function as a master amplifier of harmful signals
Rare presentation of huge ectopic ureterocele in an adult female: a case report.
Ann Med Surg (Lond)
November 2024
Article Synopsis
- Ectopic ureteroceles are rare in adults but often found in children, typically discovered during pregnancy ultrasounds or through UTI symptoms.
- A 24-year-old woman faced recurrent UTIs and severe urinary retention due to a large ectopic ureterocele, confirmed through imaging and cystoscopy.
- The minimally invasive treatment led to her full recovery and emphasizes the need to consider ectopic ureteroceles in adult women with frequent urinary issues.
Article Synopsis
- The study looked at two types of rapeseed plants, ZS758 and ZD622, to see how well they can handle stress from chromium, a heavy metal that can be harmful to plants.! -
- ZS758 did better than ZD622 under this stress because it had less harmful substances in it and worked harder to protect itself using special enzymes.! -
- The findings suggest that ZS758 is a better choice for growing in areas with chromium stress because it keeps its plant parts healthier and can better use sunlight for energy.!
Unlabelled: Fibrosis drives end-organ damage in many diseases. However, clinical trials targeting individual upstream activators of fibroblasts, such as TGFβ, have largely failed. Here, we target the leukemia inhibitory factor receptor (LIFR) as a "master amplifier" of multiple upstream activators of lung fibroblasts.
View Article and Find Full Text PDFThe purpose of this study was to determine the association of prolonged occupational co-exposure to extremely low-frequency electromagnetic fields (ELF-EMFs), noise, and rotating shift work with the levels of thyroid hormones (triiodothyronine (T3), thyroxine (T4), and thyroid-stimulating hormone (TSH). From 2016 to 2017, we enrolled all male workers without a history of thyroid disorders and followed them until 2020. To measure ELF-EMFs and noise exposures, we calculated the 8-hour equivalent sound pressure levels (Leq) and the 8-hour average of ELF-EMFs, respectively.
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