The role of wheezing subtypes in the development of early childhood asthma.

Background: Early childhood wheezing is associated with asthma risk at later ages, emphasizing the need for understanding wheezing patterns and their implications for asthma development.

Methods: Children in the F2-generation (n = 603) of the Isle of Wight Birth Cohort (IOWBC) were followed-up at 3, 6, 12, 24, 36, and 72 months. Prevalence of wheeze and wheeze type (general, infectious, and non-infectious) were recorded.

Using Unannounced Standardized Patients to Assess the Quality of Tuberculosis Care and Antibiotic Prescribing: A Cross-Sectional Study on a Low/Middle-Income Country, Pakistan.

Pakistan is classified as a high-burden country for tuberculosis, and the prescription of antibiotics and fluoroquinolones complicates the detection and treatment of the disease. The existing literature primarily relies on knowledge questionnaires and prescription analyses, which focus on healthcare providers' knowledge rather than their actual clinical practices. Therefore, this study aimed to evaluate the quality of tuberculosis care using standardized patients.

Dental management of a young patient with Papillon-Lefèvre syndrome.

This report presents the case of a girl in early adolescence with symptoms suggestive of Papillon-Lefèvre syndrome (PLS) who remained undetected with poorly managed periodontitis until the advanced stage of alveolar resorption, leading to multiple tooth loss due to periodontitis. All remaining teeth had grade III mobility and negligible alveolar support, necessitating extraction. Conventional complete dentures were provided for functional and aesthetic rehabilitation.

Trajectories of airflow limitation from childhood to early adulthood: an analysis of six population-based birth cohorts.

Background: Lung function during childhood is an important predictor of subsequent health and disease. Understanding patterns of lung function and development of airflow limitation through childhood is necessary to inform lung function trajectories in relation to health and chronic airway disease. We aimed to derive trajectories of airflow limitation from childhood (age 5-8 years) into early adulthood (age 20-26 years) using repeated spirometry data from birth cohorts.

Percutaneous Coronary Intervention for a Chronic Total Occlusion Caused by an External Pacemaker Lead Placement.

Iatrogenic injury of coronary arteries is a rare complication for which the incidence has not been reported. This paper presents the case of a 42-year-old man whose preoperative cardiac evaluation revealed a chronic total occlusion in the left anterior descending artery caused by a remote insertion of an epicardial pacemaker lead.