Basic Science and Pathogenesis.

Background: Large-scale genome-wide association studies (GWAS) of Alzheimer's disease (AD) from European ancestry identified many genetic variants associated with clinical diagnosis of AD dementia. However, it remains unclear whether these AD-related variants are associated with AD biomarkers, particularly hippocampal atrophy, a well-known neurodegeneration biomarker of AD in a Korean population. In this study, we investigated the association between known AD risk single nucleotide polymorphisms (SNPs) and hippocampal atrophy along the AD continuum in older Korean adults.

Clinical Manifestations.

Background: Numerous studies have demonstrated an association between altered liver function and Alzheimer's disease (AD) or related dementia. Nevertheless, the neuropathological substrates underlying the association remains unclear. Our aim was to investigate the association between liver function markers and the longitudinal changes of in vivo AD pathologies.

Clinical Manifestations.

Background: Disturbed sleep has been associated with Alzheimer's disease (AD) dementia. Nevertheless, limited information is yet available for the relationship between sleep experiences and longitudinal changes of brain pathologies related to AD. This study aimed to investigate the association between late-life sleep experiences and the prospective changes of in vivo AD pathologies and cerebrovascular injury over 2 years in cognitively normal (CN) old adults.

Thermal Annealing-Induced Phase Conversion in N-type Triple-Cation Lead-Based Perovskite Field Effect Transistors.

The field of perovskite optoelectronics and electronics has rapidly advanced, driven by excellent material properties and a diverse range of fabrication methods available. Among them, triple-cation perovskites such as CsFAMAPbI offer enhanced stability and superior performance, making them ideal candidates for advanced applications. However, the multicomponent nature of these perovskites introduces complexity, particularly in how their structural, optical, and electrical properties are influenced by thermal annealing─a critical step for achieving high-quality thin films.