is a major cause of community-acquired pneumonia. While studied extensively in various laboratory models, less is known about the cell function while inside the human lung. We present the first analysis of the global gene expression of while the bacteria are in the lung during pneumonia ( conditions) and contrast it with bacterial isolates that have been cultured under standard laboratory conditions ( conditions).
View Article and Find Full Text PDFPurpose: Implement a fast, motion-robust pulse sequence that acquires T -weighted, T -weighted, T -weighted, T fluid-attenuated inversion recovery, and DWI data in one run with only one prescription and one prescan.
Methods: A software framework was developed that configures and runs several sequences in one main sequence. Based on that framework, the NeuroMix sequence was implemented, containing motion robust single-shot sequences using EPI and fast spin echo (FSE) readouts (without EPI distortions).
Purpose: To synchronize and pass information between a wireless motion-tracking device and a pulse sequence and show how this can be used to implement customizable navigator interleaving schemes that are part of the pulse sequence design.
Methods: The device tracks motion by sampling the voltages induced in 3 orthogonal pickup coils by the changing gradient fields. These coils were modified to also detect RF-transmit events using a 3D RF-detection circuit.
Purpose: To enable SWI that is robust to severe head movement.
Methods: Prospective motion correction using a markerless optical tracker was applied to all pulse sequences. Three-dimensional gradient-echo and 3D EPI were used as reference sequences, but were expected to be sensitive to motion-induced B changes, as the long TE required for SWI allows phase discrepancies to accumulate between shots.