Publications by authors named "H Rosen"

Introduction: Psychotropic medication (PM) use in behavioral-variant frontotemporal dementia (bvFTD) is higher than in other dementias. However, no information exists on whether PM use differs between sporadic and genetic bvFTD.

Methods: We analyzed data from sporadic and genetic bvFTD participants with PM prescriptions in the Advancing Research and Treatment in Frontotemporal Lobar Degeneration/Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects study.

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The presence of multiple pathologies is the largest predictor of dementia. A major gap in the field is the in vivo detection of mixed pathologies and their antecedents. The Alzheimer's Disease Research Centers (ADRCs) are uniquely positioned to address this gap.

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Article Synopsis
  • Balloon angioplasty with drug-coated balloons (DCBs) is commonly used for treating in-stent restenosis, but its long-term effectiveness was not well studied until this investigation.
  • The study analyzed data from over 9,000 patients to compare DCBs, drug-eluting stents, and traditional balloon angioplasty over a 5-year period, focusing on outcomes like target-lesion revascularization and death rates.
  • Results showed that DCB angioplasty led to fewer revascularization procedures and lower overall and cardiovascular death rates compared to traditional balloon angioplasty, but it was less effective than drug-eluting stents in preventing repeat procedures.
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Reward processing involves evaluation of stimuli to inform what an individual works to pursue or avoid. Patients with behavioral variant frontotemporal dementia (bvFTD) often display reward processing changes, including insensitivity to aversive stimuli. It is unknown how early in the disease course reward changes are detectable.

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