Publications by authors named "H Rosas-Vargas"

This work presents strong evidence supporting the use of decellularized human iliac arteries combined with adipose tissue-derived stem cells (hASCs) as a promising alternative for vascular tissue engineering, opening the path to future treatments for peripheral artery disease (PAD). PAD is a progressive condition with high rates of amputation and mortality due to ischemic damage and limited graft options. Traditional synthetic grafts often fail due to poor integration, while autologous grafts may be unsuitable for patients with compromised vascular health.

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Background: Differences in Sex Development (DSD) is a heterogeneous group of congenital alterations that affect inner and/or outer primary sex characters. Although these conditions do not represent a mortality risk, they can have a severe psycho-emotional impact if not appropriately managed. The genetic changes that can give rise to DSD are diverse, from chromosomal alterations to single base variants involved in the sexual development network.

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Background: Telomere length (TL) shortening has been identified as a marker of aging and associated with adverse health outcomes, but evidence of its association with sarcopenia is inconclusive.

Aims: Estimate the cross-sectional and prospective associations between TL and sarcopenia.

Methods: We used data from Waves 3 and 4 (2017, 2021) of the Study on Global Aging and Adult Health in Mexico (SAGE-Mexico).

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There is scarce evidence on sociodemographic and lifestyle characteristics that may explain adherence to different dietary patterns (DPs) during pregnancy. Our aims were to identify dietary patterns in a sample of pregnant Mexican women and to describe their association with selected sociodemographic and lifestyle characteristics. This is a secondary cross-sectional analysis of 252 mothers of children that participated as controls in a hospital-based case-control study of childhood leukemia.

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Article Synopsis
  • The study investigates genetic alterations in pediatric B-cell Acute Lymphoblastic Leukemia (B-ALL) in Mexican patients, focusing on their impact on prognosis and treatment.
  • A total of 206 patients were analyzed, revealing a notable 21.8% prevalence of specific genetic profiles linked to poorer outcomes and indicating higher risk stratification among the affected.
  • The findings suggest that these genetic markers significantly influence overall survival, with variations in mutation frequency compared to other populations, highlighting the need for genomic considerations in treatment strategies.
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