The measurement of the liver function via the plasma disappearance rate of indocyanine green (PDR) is a sensitive bed-side tool in critical care. Yet, recent evidence has questioned the value of this method for hyperdynamic conditions. To evaluate this technique in different hemodynamic settings, we analyzed the PDR and corresponding pharmacokinetic models after endotoxemia or hemorrhagic shock in rats.
View Article and Find Full Text PDFBackground And Objective: Regular postanesthesia visits allow the detection of anesthesia related complications and increase patient satisfaction. Consequently, the performance of postanesthesia visits has been recommended after certain types of anesthesia. However, no data is available concerning the current practice of postanesthesia visits.
View Article and Find Full Text PDFPurpose: Hydroxyethyl starch (HES) may compromise renal function in critically ill patients. As an alternative, gelatin (GEL) was suggested. This study investigated whether GEL (4%) may have advantages over HES (6%, 130/0.
View Article and Find Full Text PDFBackground: Intraoperative blood salvage and processing it with commercially available devices is a widespread standard procedure to reduce allogeneic blood transfusion in patients undergoing major orthopedic surgery. The aim of this study was to investigate the impact of such processed blood on the immune system by measuring pro- and anti-inflammatory cytokines.
Study Design And Methods: Salvaged blood from 20 patients undergoing hip arthroplasty was processed with a continuous autotransfusion system.