Publications by authors named "H Ravn"
Background: Cardiogenic shock complicating acute myocardial infarction is associated with a high mortality rate. Cardiogenic shock after out-of-hospital cardiac arrest (OHCA) can be due to transient myocardial stunning but also reflect the increasing severity of ongoing heart failure. The Society for Cardiovascular Angiography and Interventions (SCAI) proposed a division of cardiogenic shock into 5 phenotypes, with cardiac arrest being a modifier.
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- * Results showed that as PEEP increased, measures of left ventricle pressure-volume area decreased significantly, indicating improved heart function in both healthy and CS states.
- * Although mean arterial pressure dropped with higher PEEP, cardiac output was maintained during LV-CS, suggesting that increasing PEEP could be a beneficial strategy in managing this condition.
The ICH E9(R1) guideline outlines the estimand framework, which aligns planning, design, conduct, analysis, and interpretation of a clinical trial. The benefits and value of using this framework in clinical trials have been outlined in the literature, and guidance has been provided on how to choose the estimand and define the estimand attributes. Although progress has been made in the implementation of estimands in clinical trials, to the best of our knowledge, there is no published discussion on the basic principles that estimands in clinical trials should fulfill to be well defined and consistent with the ideas presented in the ICH E9(R1) guideline.
View Article and Find Full Text PDFObjectives: To evaluate the impact of acute kidney injury on transition to chronic kidney disease (CKD) after cardiac surgery and to determine frequency of incident CKD in these patients.
Design: A systematic review and meta-analysis of observational studies.
Setting: Electronic databases Medline and Embase were systematically searched from 1974 to February 6, 2023.