[The effect of silybin dihemisuccinate on cholesterol biosynthesis in rat liver homogenates (author's transl)].

The effect of silybin dihemisuccinate on the hepatic biosynthesis of cholesterol was studied by measuring the incorporation of [1-14C]-acetate and [2-14C]-mevalonate in the postmitochondrial supernatant of liver homogenates. 2. Under absolute in vitro conditions, silybin dihemisuccinate inhibits the biosynthesis of cholesterol in dependence on its concentration.

[Free amino-acids of the plasma in atherosclerotic patients (author's transl)].

18 free amino-acids have been valuated in a group of patients recovering from myocardial infarction dating more than one year back and in another group of healthy active athlets. In the group of the ill persons the mean values of the following amino-acids were significantly higher: Arginine, asparagine-acid, phenylalanine, valine, lysine, serine, threonine, leucine, proline and tyrosine. While in the group of the healthy persons the following amino - acids proved to have significantly higher values: alpha -- aminobutter-acid, glycine and cystine.

[The effect of silymarin-N-methylglucamine salt and silybin-dihemisuccinate on (1-14C)-acetate incorporation in rat liver lipids (author's transl)].

60 min after i.v. application of 140.