Publications by authors named "H Rahmoune"

Article Synopsis
  • - The study examines the benefits of a peptide extract from the sea cucumber *Apostichopus japonicus* (Sample-P) in enhancing skin cell function and healing, especially under oxidative stress caused by environmental damage.
  • - Sample-P shows antioxidative properties and promotes cell migration, while also preventing severe cellular stress responses, indicated by mTOR expression levels.
  • - Proteomics analysis reveals that Sample-P affects critical protein pathways related to ribosome function and protein processing, which together help maintain DNA integrity and protect cellular components under stress, highlighting its potential for treating wounds and aging skin.
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This chapter describes the application of genomic, transcriptomic, proteomic, and metabolomic methods in the study of SARS-CoV-2 variants of concern. We also describe the important role of machine learning tools to identify the most significant biomarker signatures and discuss the latest point-of-care devices that can be used to translate these findings to the physician's office or to bedside care. The main emphasis is placed on increasing our diagnostic capacity and predictability of disease outcomes to guide the most appropriate treatment strategies.

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The appearance of new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with increased infectivity and immune escape capabilities has allowed continuation of the COVID-19 pandemic for the foreseeable future. This review describes the worldwide efforts aimed at developing new vaccination and treatment strategies to keep pace with these variants as they emerge. In the case of vaccines and monoclonal antibody-based therapeutics, we describe the development of variant-specific, multivalent, and universal coronavirus directed approaches.

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