Publications by authors named "H Radhakrishna"
Article Synopsis
- The gustatory system is responsible for detecting tastes and sending signals to the brain about what we eat, but there is limited knowledge on how this process is regulated.
- Researchers focused on the protein RGS21, believed to influence taste signaling through its role as a GTPase-accelerating protein (GAP), and conducted various analyses to understand its function in taste responsiveness.
- Their findings revealed that RGS21 is present in mouse taste buds and airway epithelial cells, and that it helps regulate bitter taste signaling by affecting changes in second messengers like cAMP and calcium.
Comment on: Central nervous system inflammatory demyelinating disorders of childhood.
Ann Indian Acad Neurol
July 2011
Acoustic cavitation-mediated wounding (i.e., sonoporation) has great potential to improve medical and laboratory applications requiring intracellular uptake of exogenous molecules; however, the field lacks detailed understanding of cavitation-induced morphologic changes in cells and their relative importance.
View Article and Find Full Text PDFActin-myosin contractility modulates focal adhesion assembly, stress fiber formation, and cell migration. We analyzed the contributions of contractility to fibroblast adhesion strengthening using a hydrodynamic adhesion assay and micropatterned substrates to control cell shape and adhesive area. Serum addition resulted in adhesion strengthening to levels 30-40% higher than serum-free cultures.
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