Current status of non-insulin-dependent diabetes mellitus (type II): management with gliclazide.

Non-insulin-dependent diabetes mellitus (NIDDM) is a major cause of morbidity and mortality worldwide, with a prevalence of 3-7% in most Western countries. Decreased insulin secretion and diminished tissue insulin sensitivity are both implicated in the pathogenesis of the disease; both may be exacerbated by persistent hyperglycemia and improved by normalization of blood sugar levels. Measures to control hyperglycemia, hypertension, and hyperlipidemia are important in the management of NIDDM and prevention of its long-term complications.

Calcification in an insulinoma of the pancreas.

Calcifications in islet cell tumors of the pancreas are rarely seen radiologically. We are reporting a case of an insulinoma with "sunburst" type calcification that has been previously described as specific for cystadenoma or cystadenocarcinoma of the pancreas.

Recognition and complications of diabetes in the older patient.

An international classification of diabetes and other disorders of glucose intolerance is presented. The disorder is subdivided into insulin-dependent diabetes mellitus (IDDM), non-insulin-dependent diabetes mellitus (NIDDM), and various forms of impaired glucose tolerance (IGT). Diagnostic criteria are discussed in detail, as are guidelines in management, including emotional support, nutritional requirements, and patient education.