Publications by authors named "H R WHITELEY"
Multidisciplinary collaboration is key to strengthening the evidence base for multifaceted illness prevention interventions. We bring together health economics and behavioral science to explore the well-being benefits and social cost-benefit of volunteer gardening at an accredited botanic garden, Wales, UK. A health economics-informed social return on investment (SROI) evaluation was combined with the assessment of volunteers' basic psychological needs (autonomy, competence, and relatedness), connection to nature, and their interrelatedness in this innovative nature-based intervention study.
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- Childhood bullying is a significant public health issue, and the KiVa program was evaluated for its effectiveness and costs in reducing bullying in schools.
- A study involving 118 primary schools randomized participants into either the KiVa intervention or a usual practice group, reporting a decrease in bullying victimization among the KiVa group and increased empathy.
- The KiVa program costs slightly more per pupil initially but shows promising results for public health regarding bullying reduction without affecting other behavioral measures significantly.
Article Synopsis
- The study explored the use of magnetic resonance elastography (MRE) as a non-invasive way to detect and measure liver fibrosis in a cancer model using Oncopigs.
- Seven Oncopigs were subjected to alcoholic liver fibrosis induction and underwent MRE imaging along with liver biopsies over three months to assess liver stiffness and fibrosis grading.
- Although MRE showed potential for detecting liver stiffness, histological analysis from biopsies was more effective in accurately identifying liver fibrosis, highlighting the need for further research in this area.
Background: Role models have been identified as a potential means to tackle the persisting low levels of physical activity among young girls. The aim of this research was to explore the involvement of community- and peer role models within the CHARMING (CHoosing Active Role Models to INspire Girls) intervention, an intervention which aims to increase and sustain physical activity among 9-10-year-old girls. The research questions were, is it feasible and acceptable to recruit role models? and what are the perceived barriers and facilitators to the inclusion of peer role models within the intervention?
Methods: A mixed methods process evaluation was embedded within a larger feasibility study, involving three secondary schools and four adjoining primary schools in South Wales, United Kingdom.
Purpose: To investigate the pharmacokinetics (PK) and early effects of conventional transarterial chemoembolization (TACE) using sorafenib and doxorubicin on tumor necrosis, hypoxia markers, and angiogenesis in a rabbit VX2 liver tumor model.
Materials And Methods: VX2 tumor-laden New Zealand White rabbits (N = 16) were divided into 2 groups: 1 group was treated with hepatic arterial administration of ethiodized oil and doxorubicin emulsion (DOX-TACE), and the other group was treated with ethiodized oil, sorafenib, and doxorubicin emulsion (SORA-DOX-TACE). Animals were killed within 3 days of the procedure.