Predictors of perioperative stroke in patients with Ischemic-type moyamoya disease treated with surgical revascularization: A retrospective multicenter study.

Introduction: Moyamoya disease (MMD) is a chronic cerebrovascular disorder characterized by progressive stenosis or occlusion of the internal carotid arteries and the development of collateral moyamoya vessels. Surgical revascularization is commonly used to prevent future ischemic events in ischemic-type MMD, but there remains a high rate of stroke perioperatively. This study aims to analyze the predictive factors for perioperative stroke in patients with ischemic-type MMD undergoing surgical revascularization using a large multicenter database.

Molecular networking guided metabolomics for mapping the secondary metabolome of six Melaleuca species and their digestive enzymes' inhibitory potential.

Melaleuca, a member of the Myrtaceae family, comprises around 300 species that are originally endemic to Australia and Southeast Asia and are cultivated as ornamental plants in Egypt. Melaleuca species are recognized as profound producers of a wide array of secondary metabolites and are valued for their essential oils which are widely used in the pharmaceutical and cosmetic industries. Yet their secondary metabolome is not fully explored.

Interventions to improve adherence/compliance to home noninvasive positive pressure ventilation in stable hypercapnic chronic obstructive pulmonary disease patients: A systematic review protocol.

Introduction: Chronic obstructive pulmonary disease (COPD) is a prevalent condition often leading to chronic hypercapnic respiratory failure in its advanced stages. Home noninvasive positive pressure ventilation (Home-NIPPV) has emerged as a key therapeutic strategy for managing stable hypercapnic COPD patients, improving survival rates, and enhancing quality of life. Despite these benefits, patient adherence/compliance to Home-NIPPV remains a significant challenge, hindered by various barriers.