Publications by authors named "H R Ramay"

Article Synopsis
  • Parkinson's disease (PD) is linked to changes in the gut microbiome, with the study aiming to identify specific microbial features related to PD onset and progression.
  • Through metagenomic sequencing of stool samples from PD patients and healthy controls, researchers found reduced intermicrobial connectivity in PD patients and identified seven bacterial species that were more or less abundant compared to controls.
  • The study suggests that these microbial changes may influence disease progression, particularly in patients with symmetric motor symptoms, and supports the notion of differing PD subtypes based on gut microbiome characteristics.
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The calf's gastrointestinal tract (GIT) microbiome undergoes rapid shifts during early post-natal life, which can directly affect calf performance. The objectives of this study were to characterise and compare differences in the establishment and succession of GIT microbiota, GIT morphological changes, and the growth of dairy calves from birth until weaned. Forty-four newborn Holstein-Friesian calves were randomly selected and assigned to Treatment (TRT) and Control (CON) groups.

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Background: The gut microbiome undergoes primary ecological succession over the course of early life before achieving ecosystem stability around 3 years of age. These maturational patterns have been well-characterized for bacteria, but limited descriptions exist for other microbiota members, such as fungi. Further, our current understanding of the prevalence of different patterns of bacterial and fungal microbiome maturation and how inter-kingdom dynamics influence early-life microbiome establishment is limited.

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Diet influences the pathogenesis and clinical course of inflammatory bowel disease (IBD). The Mediterranean diet (MD) is linked to reductions in inflammatory biomarkers and alterations in microbial taxa and metabolites associated with health. We aimed to identify features of the gut microbiome that mediate the relationship between the MD and fecal calprotectin (FCP) in ulcerative colitis (UC).

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Background: Growing evidence suggests a role for gut bacteria and their metabolites in host-signaling responses along the gut-brain axis which may impact mental health. Meditation is increasingly utilized to combat stress, anxiety, and depression symptoms. However, its impact on the microbiome remains unclear.

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