Publications by authors named "H R Nadel"
MR imaging is currently the main imaging modality used for the diagnosis and post therapeutic assessment of glioblastomas. Recently, several innovative PET radioactive tracers have been investigated for the evaluation of glioblastomas (GBM). These radiotracers target several biochemical and pathophysiological processes seen in tumors.
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- Standard testing for B-cell acute lymphoblastic leukemia (B-ALL) typically involves examining the bone marrow and cerebrospinal fluid, with imaging used in cases of suspected extramedullary disease, although not routinely for relapsed/refractory cases.
- This text discusses two patients with relapsed/refractory B-ALL who had previously received treatments and were assessed to only have minimal residual disease (MRD) before CAR-T cell therapy.
- Both patients underwent PET-MRI scans before treatment, which unexpectedly revealed significant extramedullary disease, necessitating adjustments in their clinical management and emphasizing the need for more thorough imaging studies in future B-ALL treatment protocols.
Background: Children living in poverty and those of marginalized race or ethnicity experience inferior disease outcomes across many cancers. Whether survival disparities exist in osteosarcoma is poorly defined. We investigated the association between race, ethnicity, and proxied poverty exposures and event-free and overall survival for children with nonmetastatic osteosarcoma receiving care on a cooperative group trial.
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