Arginine vasopressin (AVP) treatment increases the expression of inhibitory immune checkpoint molecules in monocyte-derived dendritic cells.

Arginine vasopressin (AVP) has disparate impacts on immune responses by divergent receptors on cells including DCs. This study was conducted with the aim of investigating the impact of AVP on the maturation and expression of the inhibitory immune checkpoint molecules in tolerogenic monocyte-derived DCs. CD14 marker was used to separate monocytes from peripheral blood mononuclear cells (PBMCs) by MACS method.

Cyclophosphamide-Induced Infertility and the Impact of Antioxidants.

An important drawback of anticancer chemotherapy is the harm it causes to healthy cells. Cyclophosphamide (CP) is a widely used chemotherapeutic alkylating agent that is regularly used in cancer treatment. However, it can cause severe side effects, including genotoxicity, due to its ability to damage DNA.

Assessment of environmental and health risks of potentially toxic elements associated with desert dust particles affected by industrial activities in Isfahan metropolitan.

Dust particles and their associated compounds can adversely affect human health and ecosystems. The aim of this study was to investigate the concentration, health, and ecological risks of selected potentially toxic elements (e.g.

Monitoring the temporal variations of plant stress using the air pollution tolerance index in the Sejzi industrial area (Isfahan, Iran).

The objective of this study was to screen air pollution-induced stress in some plant species in the Sejzi industrial region (Isfahan, Iran). An assessment of APTI and other physiological and biochemical features of significant species in the area was conducted across three seasons: spring, summer, and autumn. The physiological and biochemical factors of the following species were evaluated: Limonium persicum, Atriplex lentiformis, Nitraria schoberi, Haloxylon persicum, Tamarix hispida, Zygophyllum atriplicoides, Karelinia caspica, and Prosopis farcta.

Sperm epigenetics and male infertility: unraveling the molecular puzzle.

Background: The prevalence of infertility among couples is estimated to range from 8 to 12%. A paradigm shift has occurred in understanding of infertility, challenging the notion that it predominantly affects women. It is now acknowledged that a significant proportion, if not the majority, of infertility cases can be attributed to male-related factors.