Publications by authors named "H R Elliott"

Background: Mammography has poor sensitivity in dense breast tissue. Retrospective studies suggest that Molecular Breast Imaging (MBI), has superior diagnostic accuracy to mammography in women with very dense breast tissue. Women's perspectives of MBI are unknown, but are crucial to understanding the feasibility of, and routes to, adoption into practice.

View Article and Find Full Text PDF

Context.—: Precise determination of biomarker status is necessary for clinical trial enrollment and endpoint analyses, as well as for optimal treatment determination in real-world practice. However, variabilities may be introduced into this process due to the processing of clinical specimens by different laboratories and assessment by distinct pathologists.

View Article and Find Full Text PDF
Article Synopsis
  • - Children born via cesarean delivery have a greater risk of various health issues compared to those born vaginally, but the exact reasons are still not fully understood.
  • - A meta-analysis involving over 12,000 participants found six specific DNA methylation markers in newborns linked to cesarean delivery, but these markers did not persist into childhood.
  • - The study indicates that cesarean delivery affects certain blood cell proportions at birth, but further research is necessary to understand its long-term impacts on child health.
View Article and Find Full Text PDF

As stresses on groundwater resources increase due to growing population and climate change, water litigation, such as the recently decided Mississippi (MS) vs Tennessee (TN) lawsuit, will become more common. In the United States, lawsuits between states can be heard only by the Supreme Court of the United States (SCOTUS). These lawsuits are expensive and lengthy, often requiring highly specialized technical expertise.

View Article and Find Full Text PDF
Article Synopsis
  • - Clinical trials for metabolic dysfunction-associated steatohepatitis (MASH) need accurate histologic scoring to assess participants and outcomes, but varying interpretations have affected results.
  • - The AI-based tool AIM-MASH showed strong consistency and agreement with expert pathologists in scoring MASH histology, achieving accuracy comparable to that of average pathologists.
  • - AIM-MASH demonstrated a strong ability to predict patient outcomes, correlating well with pathologist scores and noninvasive biomarkers, indicating it could enhance the efficiency and reliability of clinical trials for MASH.
View Article and Find Full Text PDF