Publications by authors named "H R El-Khayat"

Pollutants and parasites represent stressors for fish at the individual, population, or community levels. The current study outlines the seasonal infestation pattern of Oreochromis niloticus by protozoan and helminths parasites linked to some physicochemical parameters (pH, dissolved oxygen, total dissolved solids, and electrical conductivity), and metals (Cd, Pb, Fe, Zn, and Ca), at nine selected sites in River Nile (Greater Cairo area) from summer 2019 till spring 2020. Most of the studied criteria in Nile water samples showed normal levels during all seasons compared to the recommended limits of EPA.

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Article Synopsis
  • The study evaluates the effects of the Lake Manzala development, initiated in 2017, on factors like water quality and biomarkers in fish (Oreochromis niloticus) and snails (Biomphalaria alexandrina) sampled in 2021, comparing them to results from 2015.
  • Results showed improved water quality, with increased electrical conductivity, reduced heavy metal contamination (Pb, Cd, Cu, Zn), and better overall health indicators in fish and snails, indicating a biologically improved environment.
  • Histopathological assessments revealed better tissue conditions in fish and snails from Port Said compared to Dakahlia, while immune responses indicated more inflammation in Dakahlia, suggesting
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Continuous field studies on the abundance and distribution of freshwater snails and cercarial populations are important for schistosomiasis control programs. In the present work, snail surveys and cercariometry were conducted for four successive seasons at 12 sites on the Nile River banks in the area of Greater Cairo to identify potential transmission foci for schistosomiasis. In addition, water physicochemical parameters were recorded.

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Background: Reactivation of hepatitis B virus (HBV) infection in patients treated for chronic hepatitis C (HCV) with direct-acting antiviral agents has emerged recently as an important safety issue; however, it has not been adequately studied in pediatric age groups. We aimed to evaluate this risk in adolescent patients infected with chronic HCV and positive for HBsAg and HBcAbs.

Patients And Methods: One hundred and fifteen adolescent patients from 12 to 17 years of age, infected with chronic HCV and positive for HBcAbs with or without HBsAg were included in this study.

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Background & Aims: Treatment of children aged 3-6 genotype 4 is still limited by the interferon side effects. We aimed in this study to evaluate the effectiveness and safety of sofosbuvir/ledipasvir in children (3-6 years) genotype 4 chronic HCV-infected patients.

Methods: In total, 22 consecutive chronic HCV-infected patients (mean age 4.

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