Neuron-specific enolase and S-100B are associated with neurologic outcome after pediatric cardiac arrest.

Objective: To characterize the pattern of serum biochemical markers of central nervous system injury (neuron-specific enolase [NSE], S-100B, plasminogen activator inhibitor-1 [PAI-1]) after pediatric cardiac arrest and determine whether there is an association between biomarker concentrations and neurologic outcome.

Design: Prospective, observational study.

Setting: Urban, tertiary care children's hospital.

Removal of gadolinium by peritoneal dialysis.

An association between gadolinium-containing contrast and the development of nephrogenic systemic fibrosis (NSF) has been increasingly recognized. For patients receiving hemodialysis (HD) who are exposed to gadolinium, the Federal Drug Administration (FDA) recommends HD to remove this contrast agent in order to minimize the risk of NSF. This study examines if gadolinium can be removed by frequent exchanges by peritoneal dialysis (PD).

Association of timing, duration, and intensity of hyperglycemia with intensive care unit mortality in critically ill children.

Objective: To study the association of timing, duration, and intensity of hyperglycemia with pediatric intensive care unit (PICU) mortality in critically ill children.

Design: Retrospective cohort study.

Setting: PICU of a university-affiliated, tertiary care, children's hospital.

S-100beta protein--serum levels in children with brain neoplasms and its potential as a tumor marker.

Objective: To determine if serum S-100beta levels are elevated in children with brain neoplasms and if it can be used as a tumor marker for children with brain neoplasms.

Design: Prospective cohort study.

Setting: Urban, tertiary care, children's teaching hospital.

Cerebrospinal fluid levels of S-100beta in children and its elevation in pediatric meningitis.

Objective: To describe normal cerebrospinal fluid (CSF) levels of S-100beta in children and determine whether CSF S-100beta levels are elevated in pediatric meningitis.

Design: Cohort study.

Setting: Children's teaching hospital.