Middle-age and older runners demonstrate differences in running biomechanics compared with younger runners. Female runners demonstrate differences in running biomechanics compared with males, and females experience hormonal changes during menopause that may also affect age-related changes in running biomechanics. The purpose of this study was to determine the relationship between age and running biomechanics in healthy female recreational runners.
View Article and Find Full Text PDFObjective: This study aimed to systematically investigate whether polarized or non-polarized training leads to greater physiological and performance adaptations in cyclists.
Design: A systematic review and meta-analysis were conducted, focusing on interventions categorized as polarized, non-polarized, or unclear. Inclusion criteria required participants to be at least recreationally trained cyclists (VO ≥ 59 ml/kg/min) and interventions lasting > 4 weeks.
This study examined nine prominent commercially available single-cell RNA sequencing (scRNA-seq) kits across four technology groups. Each kit was characterized using peripheral blood mononuclear cells (PBMCs) from a single donor, which enabled consistent assessment of factors such as analytical performance, protocol duration and cost. The Chromium Fixed RNA Profiling kit from 10× Genomics, with its probe-based RNA detection method, demonstrated the best overall performance.
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