[The Beginning of the End: Sars-Cov-2 Vaccines].

En Berkeley Inglaterra en1749 nace Edward Jenner, el hombre que cambió la historia de la medicina. En 1796 ya siendo médico visitaba tambos y observaba con espíritu crítico, las pústulas de las ordeñadoras ocasionadas por la viruela vacuna. En esa época morían anualmente en el mundo 9 millones de personas.

[Enterobius vermicularis enteroparasite role in appendicitis cecal: Enterobiasis and appendicitis].

Sixty-five cases of enterobiasis of the cecal appendix are reported by Enterobius vermicularis or Oxiurus vermicularis. Enterobiasis is a cosmopolitan parasite5,8,13 and frequent. It is useful to establish whether it can cause appendicitis and the mechanisms involved.

Regulation of parathyroid hormone-related peptide by estradiol: effect on tumor growth and metastasis in vitro and in vivo.

We evaluated the capacity of estradiol (E(2)) to regulate PTHrP production, cell growth, tumor growth, and metastasis to the skeleton in breast cancer. In estrogen receptor (ER)-negative human breast cancer cells, MDA-MB-231, and cells transfected with full-length cDNA encoding ER (S-30), E(2) caused a marked decrease in cell growth and PTHrP production, effects that were abrogated by anti-E(2) tamoxifen. E(2) also inhibited PTHrP promoter activity in S-30 cells.

[Toxoplasmic retinochoroiditis reactivated in the puberty].

By a clinical-infectious and ophthalmologic examination that includes serologic studies, we found that 17 cases of retinochoroiditis reactivated in the puberty.

[Larva migrans syndrome or ocular toxocariasis].

Thirteen cases of ocular toxocariasis attended in the Oftalmology Service of the Pediatric Hospital "Niño Jesús", from Córdoba; and in the Parasitology and Micology Cathedra of the Medicine Collegue of the University of Córdoba were studied from July 1993 till July 1995. The authors determine the needs of taking into account this parasitosis; above all in children and with the antecedent of contact with pets.