[Global ophthalmology : Update].

The aim of global ophthalmology is to maximize vision, ocular health and functional ability, thereby contributing to overall health and well-being, social inclusion and quality of life of every individual worldwide. Currently, an estimated 1.1 billion people live with visual impairment, 90% of which can be prevented or cured through largely cost-effective interventions.

Artificial intelligence-supported diabetic retinopathy screening in Tanzania: rationale and design of a randomised controlled trial.

Introduction: Globally, diabetic retinopathy (DR) is a major cause of blindness. Sub-Saharan Africa is projected to see the largest proportionate increase in the number of people living with diabetes over the next two decades. Screening for DR is recommended to prevent sight loss; however, in many low and middle-income countries, because of a lack of specialist eye care staff, current screening services for DR are not optimal.

XEN-45 implantation for refractory uveitic glaucoma.

Purpose: To evaluate the efficacy of XEN-45 gel stent ab interno implantation for medically uncontrolled uveitic glaucoma.

Methods: Retrospective analysis of 25 eyes receiving XEN gel stent for medically uncontrolled uveitic glaucoma from February 2019 to February 2023 with recording of intraocular pressure (IOP) values, ocular hypotensive medication, requirement for revision or secondary surgery and complications. Prerequisites for XEN implantation were a clear cornea, an open iridocorneal angle and an unscarred, mobile conjunctiva at the implantation site.

XEN-63 Compared to XEN-45 Gel Stents to Reduce Intraocular Pressure in Glaucoma.

The XEN gel stent reduces intraocular pressure (IOP) in glaucoma. XEN-45 is widely used; the newer XEN-63 has a larger lumen targeting potentially lower IOP outcomes. We retrospectively compared the first 15 XEN-63 cases to 15 matched XEN-45 controls.

Differentiating stages of functional vision loss from glaucoma using the Disc Damage Likelihood Scale and cup:disc ratio.

Background: Glaucoma staging is critical for treatment planning but has rarely been tested in severe/end-stage disease. We compared the performance of the Disc Damage Likelihood Scale (DDLS) and cup:disc ratio (CDR) using a functional glaucoma staging system (GSS) as the reference standard.

Methods: Post hoc analysis of a randomised controlled trial at the Eye Department of Kilimanjaro Christian Medical Centre, Tanzania.