Prognostic and predictive molecular biological markers in prostate cancer - significance of expression of genes PCA3 and TMPRSS2.

Unlabelled: Prostate specific antigen and digital rectal examination have low specificity for detecting prostate cancer and they poorly predict the presence of aggressive disease. We present recent findings on PCA3 and TMPRSS:ERG fusion and assessed the relationship between PSA, urine PCA3 and TMPRSS2:ERG and corelation with pathological findings. We tested the PCA3 score in two groups.

Radiotherapy in the treatment of epididymal adenocarcinoma - case report.

Background: Primary epididymal carcinoma is an extremely rare disease with a bad prognosis. We describe the first report of radiotherapy for definitive treatment of such a tumour.

Case Report: A 35-year-old man with a tumour of the epididymis underwent orchiectomy and elective retroperitoneal lymphadenectomy.

Long term results of HDR brachytherapy in men older than 75 with localized carcinoma of the prostate.

Background: Prostate cancer is an illness with a high incidence, especially among older men. The choice of a treatment option among men above 75 years is, however, not clear. Radical prostatectomy in this age group is connected with a relatively high morbidity.

[The role of permanent brachytherapy in the treatment of localized prostate carcinoma].

The popularity of permanent brachytherapy is now growing dramatically. The development of several new technologies has led to an improvement in dose distribution and results and can also return the patients to normal daily activities. The role of permanent brachytherapy in the treatment of localized prostate carcinoma is described in the present article.

[The role of interstitial brachytherapy in multimodality management of solid tumors].

Although being used for several decades, interstitial brachytherapy remains a modern radiotherapeutic method. Over the time, it has been highly improved, including the latest technologies. Its broad use has been facilitaed by the use of high dose rate (HDR) afterloadings.