Publications by authors named "H Pascalis"
Dengue virus has recently reemerged in the southern Indian Ocean islands, causing outbreaks in Reunion Island and the Seychelles. In the present study, we determined the complete genome sequences of closely related clinical isolates of dengue virus type 2 circulating in the Seychelles in 2016 and Reunion Island in 2018.
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- - The study aimed to assess the exposure to Hepatitis E virus (HEV) on Reunion Island using a serosurvey among blood donors, analyzing archived frozen sera from a past cohort.
- - Results showed raw and weighted seroprevalences of HEV at 9.01% and 6.73%, respectively, with higher seropositivity observed in older individuals and males compared to females.
- - Findings suggest that Reunion Island has low endemicity for HEV, with spatial variability linked to living near pig farms, hinting at potential environmental contamination as a risk factor.
Objective: Murine typhus has been increasingly reported on Reunion island, Indian ocean, following documentation of eight autochthonous infections in 2012-2013. We conducted a serosurvey to assess the magnitude of the seroprevalence of rickettsioses in the population. Two hundred and forty-one stored frozen sera taken from the 2009 Copanflu-RUN cohort were analysed using an immunofluorescence assay allowing to distinguish typhus group (TGR) and spotted fever group Rickesttsiae (SFGR).
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- * Results showed a weighted seroprevalence of 6.81%, with no infections found in individuals under 20, indicating exposure isn't influenced by age or gender.
- * Higher exposure rates were found in areas with ruminant farms, suggesting that Q fever is endemic to the island with spatial distribution linked to agriculture.
Reunion Island is currently experiencing an epidemic caused by Dengue virus type-2 (DENV-2) resulting in over 6,763 cases from austral summer 2017 to winter 2018. Phylogenetic analyses on two non-imported cases of dengue infection from Reunion Island highlight a regional circulation of DENV-2 Cosmopolitan lineage 1 virus on both Reunion Island and the Seychelles.
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