IGF2BP3 is upregulated in endometrial cancer and tightly regulates the growth of drug-resistant endometrial cancer cells via HMGA1.

Objective: Endometrial cancer (EC) is a malignant tumor with various histological subtypes and molecular phenotypes. The evaluation of drug resistance is important for cancer treatment. Progesterone resistance is the major challenge in EC.

Transitioning from perceived stress to mental health: The mediating role of self-control in a longitudinal investigation with MRI scans.

Background: The neural mechanisms and long-term effects of perceived stress (PS) and self-control (SC) on mental health (MH) are not fully understood. This study seeks to investigate the influence of PS and SC on MH and to identify their neural correlates using fMRI.

Methods: A total of 817 college students participated in behavioral assessments, including the Perceived Stress Scale (PSS), Self-Control Scale (SCS), and Mental Health Continuum Short Form (MHC-SF).

Integrating single-cell RNA-seq and bulk RNA-seq to explore prognostic value and immune landscapes of methionine metabolism-related signature in breast cancer.

Background: Neoadjuvant, endocrine, and targeted therapies have significantly improved the prognosis of breast cancer (BC). However, due to the high heterogeneity of cancer, some patients cannot benefit from existing treatments. Increasing evidence suggests that amino acids and their metabolites can alter the tumor malignant behavior through reshaping tumor microenvironment and regulation of immune cell function.

 (Acoraceae), a new species from Southern China.

(Acoraceae) is a commonly used seasoning in southern China. It was previously misidentified as (Yamam.) F.

Application value of different imaging methods in the early diagnosis of small hepatocellular carcinoma: a network meta-analysis.

Objective: To determine the diagnostic value of ultrasound, multi-phase enhanced computed tomography, and magnetic resonance imaging of small hepatocellular carcinoma.

Methods: Experimental studies on diagnosing small hepatocellular carcinoma in four databases: PubMed, Cochrane Library, Web of Science, and Embase, were comprehensively searched from October 2007 to October 2024. Relevant diagnostic accuracy data were extracted and a Bayesian model that combined direct and indirect evidence was used for analysis.