[Plea for a work policy aiming autonomy and recovery in child and adolescent psychiatry].

When a child or adolescent is admitted to a High & Intensive Care (HIC) unit for adolescents, this implies that they find themselves in a severe psychiatric crisis. The work policy aiming autonomy and recovery is a vision that has been implemented in the treatment method at the HIC unit for adolescents. This policy focuses on the recovery of young people, in which learning to understand their own story and learning taking responsibility, are essential components.

Automated and cost-efficient early detection of hemolysis in patients with extracorporeal life support: Use of the hemolysis-index of routine clinical chemistry platforms.

Purpose: Patients with extracorporeal life support (ECLS) are at risk for hemolysis-related complications. Therefore, monitoring of free hemoglobin (fHb) levels is indicated. Conventional methods for fHb are laborious and not always available.

Autofluorescence distribution along the corneal axis in diabetic and healthy humans.

Corneal autofluorescence, as measured with a commercial scanning fluorophotometer (lambda(exc): 415-491 nm; lambda(em): 515-630 nm), is increased in patients with diabetes mellitus. However, such fluorophotometers register an average fluorescence signal over all corneal layers as a consequence of their limited axial resolution of 0.5 mm.

Evaluation of diabetic retinopathy by fluorophotometry. European concerted action on ocular fluorometry.

Background: Fluorophotometric variables (permeability of the blood-retinal barrier (BRB) and blood-aqueous barrier (BAB), corneal autofluorescence, and lenticular light transmittance) are reported to correlate with the severity of diabetic retinopathy. This preliminary multicenter study was performed to measure these variables simultaneously in patients with type 2 diabetes mellitus and to assess which of these variables could be of help in evaluating diabetic retinopathy.

Methods: Eighty-two patients with type 2 diabetes and diabetic retinopathy were recruited in seven European university clinics.

Autofluorescence of the diabetic and healthy human cornea in vivo at different excitation wavelengths.

Corneal autofluorescence is higher in diabetes mellitus patients with retinopathy than in healthy subjects. In this study, the excitation spectra of corneal autofluorescence of diabetic patients and healthy controls in the range 365 nm-480 nm were compared in an attempt to identify the fluorophores responsible for corneal autofluorescence in health and disease (diabetes). Spectral measurements (from one eye) were recorded from five patients with proliferative diabetic retinopathy and five age-matched healthy controls, using a modified commercial scanning fluorophotometer with a mercury arc or a tungsten halogen lamp as excitation light source in combination with interference filters (excitation wavelengths: 365, 405, 420, 430, 436, 440, 450, 470 and 480 nm; bandwidth: 10 nm).