"Development, optimization, and characterization of Eudragit-based nanoparticles for Dasatinib delivery".

This study focused on developing and evaluating dasatinib-loaded nanoparticles (DST-NPs) using Eudragit L100 as a polymer matrix for enhanced breast cancer treatment. The optimized formulation exhibited a particle size of 202.1 ± 5.

A new bi-level TOPSIS based neutrosophic programming technique for land allocation to medium farm holders.

Agriculture impacts a country's social and economic growth. Crop allocation, crop combinations, and crop production processes are all necessary to achieve optimal results during various growing seasons. To maximize farm earnings, proper farm planning and resource allocations are necessary.

Vaginal Delivery in a Tracheostomised Woman: A Rare Case Scenario.

Spontaneous vaginal delivery in a tracheostomised woman is rare and literature concerning the same is also very limited, hence this might help in considering vaginal delivery at term as an option in such patients when there are no medical or obstetrical contraindications for the same. We present a case of a 24 years female patient hailing from Tamil Nadu in South India, who was tracheostomised secondary to subglottic stenosis, presented to Otorhinolaryngology department at thirty-eight weeks of gestation to know the possibility of a vaginal delivery at term. Since the patient had an uneventful obstetrical history and no medical or obstetrical contraindications for a vaginal delivery, patient was advised breathing exercises including Valsalva manoeuvre and kept under close follow up.

Development and Characterization of Sulfasalazine Cubosomes for Potential Transdermal Drug Delivery.

Background: Rheumatoid arthritis is indeed a constant, progressive autoimmune disease that acts on the synovial membrane, distinguished by joint pain, swelling, and tenderness. Sulfasala- zine belongs to BCS Class IV having low solubility and low permeability. To overcome the issue and provide a localized effect Cubosomes were chosen for the transdermal drug delivery system.

Early detection of emerging persistent perfluorinated alkyl substances (PFAS) along the east coast of India.

Perfluorooctanoic acid (PFOA) and Perfluorooctane sulfonate (PFOS) are resistant to breakdown and are now considered global contaminants. However, interest in these recalcitrant compounds among scientists and legislators has grown significantly in recent years. In the present study, we analyzed the level of PFOA and PFOS contamination in surface water from the coastal regions of Tamil Nadu and West Bengal.