Publications by authors named "H P Gloser"

History And Admission Findings: A 42-year-old man who had just returned from a trip to Turkey presented with recurrent right upper abdominal pain and bouts of fever. Physical examination was unremarkable except for an enlarged liver on palpation.

Investigations: There was a slight increase in tests indicating cholestasis and in transminases.

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Immunoglobulin therapy is becoming an important modality for the prevention and treatment of bacterial and viral infection. Standard intravenous immunoglobulin (IVIG) is made from large pools of plasma obtained from normal blood donors. However, lot-to-lot variation in titers of antibody to specific microbial pathogens may diminish therapeutic efficacy.

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IGIV appears to have a promising future in treating and perhaps preventing neonatal bacterial infections. However, all IGIV lots do not contain equal amounts of pathogen-specific IgG with functional opsonic activity. To ensure effective therapy it will be important to inform physicians that the IGIV lots available for use contain functional antibacterial antibody to the responsible pathogens.

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