Publications by authors named "H P Dijkstra"
We address the issue of resilience of the Atlantic Meridional Overturning Circulation (AMOC) given the many indications that this dynamical system is in a multi-stable regime. A novel approach to resilience based on rare event techniques is presented, which leads to a measure capturing "resistance to change" and "ability to return" aspects in a probabilistic way. The application of this measure to a conceptual model demonstrates its suitability for assessing AMOC resilience but also shows its potential use in many other non-autonomous dynamical systems.
View Article and Find Full Text PDFObjective: To report a 3-year follow-up from the FemoroAcetabular Impingement Trial, comparing arthroscopic surgery with physiotherapy in the management of femoroacetabular impingement (FAI) syndrome for the dual primary outcomes of radiographic hip osteoarthritis (OA) and patient-reported outcome measures of activities of daily living.
Methods: Two-group parallel, assessor-blinded, pragmatic randomised controlled trial across seven sites. 222 participants aged 18-60 years with FAI syndrome confirmed clinically and radiologically were randomised (1:1) to receive arthroscopic hip surgery (n=112) or physiotherapy (n=110).
Rationale: The role of the innate immune system in polycystic liver disease (PLD) has been underexplored despite its potential importance in disease progression. This study explores the innate immune response in PLD patients by analyzing cytokine production of peripheral blood mononuclear cells (PBMCs) in response to various pathogens compared to healthy controls.
Methods: Samples were collected from patients with ADPLD or ADPKD and PLD.
Article Synopsis
- The Earth is warming due to human-caused greenhouse gas emissions, which may lead to critical climate changes like the weakening of the Atlantic Meridional Overturning Circulation (AMOC).
- Researchers used the Community Earth System Model (CESM2) to analyze how AMOC weakening affects atmospheric carbon dioxide (pCO2) under different emission scenarios from 2015 to 2100.
- They found a slight increase in pCO2 in response to AMOC weakening, with local climate and carbon cycle changes that could significantly impact ecosystems and society, despite overall global effects being small.