Publications by authors named "H P Baer"
Objective: The objective of this study was to describe the prevalence of obesity, obesity-related conditions (ORCs), and antiobesity medication (AOM) eligibility and prescribing practice among eligible patients in a large health care system.
Methods: In this cross-sectional analysis of the multicenter Mass General Brigham health care system (Boston, Massachusetts) spanning 2018 to 2022, adults eligible for AOMs (BMI ≥ 30 kg/m or BMI 27-29.9 kg/m with ≥1 ORC) were identified.
Objective: Callous-unemotional (CU) behaviors and quantitative autistic traits (QATs), heritable domains implicated in social development, are both associated with reduced prosocial behavior and increased aggression at their clinical extremes. However, they are hypothesized to contribute to aggression through separate mechanisms. This study tested whether CU behaviors and QATs exhibited distinct profiles of heritable influences as well as independent contributions to early childhood aggression in a general population sample with enhanced sensitivity to clarify these relationships.
View Article and Find Full Text PDFCharacterization and Incidence of Sunflower Seed Allergy in a Pediatric Allergy Clinic.
J Allergy Clin Immunol Pract
November 2024
Article Synopsis
- Sunflower seeds are increasingly recognized as a common allergen-free alternative to peanuts, but they can also cause allergies.
- A study conducted over 26 years identified 235 pediatric patients with sunflower seed allergy, primarily diagnosed at around 3.9 years old, and most had other related allergy conditions.
- The study found that the incidence of sunflower seed allergies rose over time, with an annual increase of 21%, and reactions often ranged from mild skin issues to severe anaphylactic responses.
Article Synopsis
- The study evaluated immune responses to COVID-19 vaccines in adults aged 50 and older by measuring antibody levels and T-cell responses after a two-dose series.
- Vaccinated individuals with mRNA/mRNA and ChAdOx1-S/mRNA regimens showed higher antibody responses compared to those receiving the ChAdOx1-S/ChAdOx1-S regimen, peaking one month after the second dose.
- It suggests that both antibody concentration and avidity should be factored in when assessing COVID-19 vaccine protection.
The standard surgical procedure for abdominal hernia repair with conventional prosthetic mesh still results in a high recurrence rate. In the present study, we propose a fibroblast matrix implant (FMI), which is a three-dimensional (3D) poly-L-lactic acid scaffold coated with collagen (matrix) and seeded with fibroblasts, as an alternative mesh for hernia repair. The matrix was seeded with fibroblasts (cellularized) and treated with a conditioned medium (CM) of human Umbilical Cord Mesenchymal Stem Cells (hUC-MSC).
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